SULFONYLAMINOCARBOXYLIC ACID SULFUR-SUBSTITUTED N-ARYLAMIDES, METHOD FOR THEIR PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT Russian patent published in 2004 - IPC

Abstract RU 2234497 C2

FIELD: organic chemistry, chemical technology, medicine, pharmacy.

SUBSTANCE: invention relates to sulfonylaminocarboxylic acid sulfur-substituted N-arylamides of the formula (I):

wherein A¹ means phenylene, thiazolylene and benzothiazolylene being phenylene can be substituted; ring A² that comprises carbon atoms and represents benzene ring or aromatic monocyclic 5-6-membered heterocycle comprising one or two ring heteroatoms taken among nitrogen (N), oxygen (O) and sulfur (S) atoms. Compounds are valuable pharmaceutically active compounds used for treatment and prophylaxis of diseases, for example, cardiovascular diseases. Except for, invention relates to methods for preparing compounds of the formula (I), their using for treatment and prophylaxis of above indicated diseases, and for preparing pharmaceutical preparation designated for this purposes and to pharmaceutical preparations comprising compounds of the formula (I).

EFFECT: improved preparing method, valuable medicinal and pharmaceutical properties of compounds.

20 cl, 246 ex

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RU 2 234 497 C2

Authors

Shindler Urzula

Shenafinger Karl

Shtrobel' Khartmut

Dates

2004-08-20—Published

1999-06-25—Filed