METHOD FOR PRODUCING HIGHLY VIRUS-SAFETY COMPONENTS FOR PREPARING FIBRIN GLUE FROM HUMAN PLASMA BLOOD POOL Russian patent published in 2004 - IPC

Abstract RU 2236237 C2

FIELD: biotechnology, medicine.

SUBSTANCE: invention relates to a method for preparing components of biological glue from plasma blood pool that give in together highly qualitative virus-safety product with the high yield. Product comprising triply inactivated viruses and no containing fibrinogen, fibronectin and factor XIII is prepared firstly by treatment of its concentrate with virucidal solution of solvent/detergent and then by nanofiltration of viruses and, finally, by thermal treatment. Method of invention doesn't effect on the yield highly qualitative product. Invention provides the improvement of the known patented method with elevating yield of active thrombin by about two-fold.

EFFECT: improved producing method, high yield of product.

16 cl, 4 dwg, 1 ex

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RU 2 236 237 C2

Authors

Bui-Khak Trung

Dates

2004-09-20Published

1998-10-29Filed