FIELD: biotechnology, medicine.
SUBSTANCE: invention relates to a method for preparing components of biological glue from plasma blood pool that give in together highly qualitative virus-safety product with the high yield. Product comprising triply inactivated viruses and no containing fibrinogen, fibronectin and factor XIII is prepared firstly by treatment of its concentrate with virucidal solution of solvent/detergent and then by nanofiltration of viruses and, finally, by thermal treatment. Method of invention doesn't effect on the yield highly qualitative product. Invention provides the improvement of the known patented method with elevating yield of active thrombin by about two-fold.
EFFECT: improved producing method, high yield of product.
16 cl, 4 dwg, 1 ex
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Authors
Dates
2004-09-20—Published
1998-10-29—Filed