METHOD OF CLEANING THROMBIN SOLUTION FROM INFECTIOUS PARTICLES Russian patent published in 2012 - IPC C07K1/34 C07K14/475 C07K14/54 C07K14/555 

Abstract RU 2468032 C2

FIELD: chemistry.

SUBSTANCE: invention relates to biochemistry. A method of cleaning thrombin solution from infectious particles is provided. Macromolecules are added to the starting thrombin solution. The obtained solution is then passed through a nanofilter to obtain a thrombin solution free from infectious particles. Said macromolecule is not a nonionic surfactant, is different from thrombin and can be selected from a polymer containing at least 3 monomers of sugar, amino acids, glycols, alcohols, lipids or phospholipids. A thrombin-containing solution obtained using said method is also provided.

EFFECT: invention increases efficiency of removing infectious particles from thrombin solution; thrombin output reaches 93% using said method.

20 cl, 2 dwg, 13 tbl

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RU 2 468 032 C2

Authors

Mintts Roni

Nur Izraehl'

Dates

2012-11-27Published

2007-06-25Filed