METHODS FOR PREPARING COMPOUNDS OF ORTHO-NITROBENZONITRILE (VARIANTS) Russian patent published in 2004 - IPC

FIELD: organic chemistry, chemical technology, pesticides.

SUBSTANCE: invention relates to new methods (variants) for preparing intermediate compounds, in particular, 4-cyano-3-nitrobenzofluoride, that can be used in preparing pesticides. Invention relates also to methods for preparing compound of the formula (I):

wherein R¹ means (C₁-C₄)-halogenalkyl; R² means hydrogen atom, (C₁-C₄)-alkoxy-group. Methods involve interaction of the corresponding ortho-nitrohalogenbenzene of the formula (II):

wherein R¹ and R² have values indicated above; X represents fluorine or bromine atom: with (a) alkaline metal cyanide in anhydrous solvent being optionally in the presence of a catalyst in the case when X means fluorine atom; or (b) with alkaline metal cyanide in the presence of catalytic amount of copper (I) cyanide and interphase catalyst in the case when X means bromine atom, or interaction of the corresponding ortho-nitrohalogenbenzene of the formula (II) with copper (I) cyanide being optionally in the presence of catalyst taken among alkaline or alkaline-earth metal bromide. Method provides preparing compound of ortho-nitrobenzonitrile with high yield and/or high selectivity.

EFFECT: improved preparing methods.

19 cl, 14 tbl, 12 ex