FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention describes compounds or their salts of the following general formula (I): A-B-C-N(O)2 (I) wherein A means R-T1 wherein R represents radical of medicinal agent as determined in the invention claim; T1 means (CO), oxygen (O), sulfur (S), nitrogen (N) atom or NR1C wherein RC represents hydrogen atom (H) or (C1-C5)-alkyl; B means -TB-X-TBI wherein TB and TI are similar or different and taken among (CO), oxygen (O), sulfur (S), nitrogen (N) atom or NR1C wherein RC1 is determined above; X2 represents bivalent bridge group such as corresponding precursor of B, such as determined in the invention claim; C represents bivalent radical -TC-Y-, wherein TC means (CO), oxygen (O), sulfur (S), nitrogen (N) atom or NR1C wherein R1C is such as determined above; Y has values as represented in the invention claim. Also, invention describes a pharmaceutical composition based on compounds of the formula (I) used in oxidative stress and/or endothelial dysfunctions. Invention provides preparing new compounds and their salts eliciting useful biological properties.
EFFECT: valuable medicinal properties of compounds.
6 cl, 8 tbl, 28 ex
