FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to new nitrate salts of compounds of formulas taken among the following classes: class F1):
(I) (F1a) disodium alendronate; class F2A):
(II) (F2AIV) piroxicam;
(III) (F2AXV) methotrexate;
(IV) (F2AXVI) penicillamine;
(V) (F2AXVII) tramadol; class F2B:
(VI) (F2B1) tomoxiprol that can be use in medicine for treatment of osseous injures, such as injures in osseous tissue and articulations. Indicated compounds show the enhanced therapeutic activity and improved gastrointestinal tolerance as compared with bases of formulas (I)-(VI).
EFFECT: valuable properties of compounds.
5 cl, 5 tbl, 14 ex
