DERIVATIVES OF BENZODIOXOL, BENZOFURAN, DIHYDROBENZOFURAN AND BENZODIOXANE AND COMPOSITIONS COMPRISING THEREOF Russian patent published in 2002 - IPC

Abstract RU 2190609 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to novel derivatives of benzodioxol, benzofuran, dihydrobenzofuran and benzodioxane or their pharmaceutically acceptable solvates of the general formula (I): where Q1 and Q2 each means independently hydrogen or halogen atom; X means CH2, CH or O-atom; Y means CR2 or CR3, CR3R4 where n = 1-4; Z means (CH2)n, CH or O-atom; R means hydrogen, halogen atom or CH2-alkyl in both cases; m = 1 or 2; C1-4 means R1-alkyl, C1-6-cycloalkyl, C3-6-haloidalkyl, C1-3-alkylamino-group, C1-6-alkenyl, C2-6-alkoxy-C1-4-alkyl, C1-4-alkylthio-C1-C4-alkyl or trifluoromethylalkyl-C1-4,; R2 means hydrogen, halogen atom or C1-4-alkyl; and R3 and R4 each means independently hydrogen atom or C1-4-alkyl. Invention relates to pharmaceutical compositions comprising said compounds used for therapy of sleep disorders and disorders associated with circadian rhythm impairment. EFFECT: valuable medicinal properties. 17 cl, 2 tbl, 102 ex

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RU 2 190 609 C2

Authors

Kehtt Dzhon D.

Dzhonson Grehkhehm

Kivaj Dehniehl Dzh.

Mehttson Ronald Dzh.

Parker Majkl F.

Tehkaki Kehtrin S.

Jevich Dzhozef P.

Dates

2002-10-10Published

1997-12-09Filed