NITROXY-DERIVATIVE SALTS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF Russian patent published in 2004 - IPC

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention describes organic or inorganic salts of compounds of the general formula: A-X₁-N(O)_z where z means a whole number and means 1 or 2; A means R(COX_u)_t wherein t and u mean a whole number and mean 1; X means oxygen atom (O); X₁ means compound of the formula:

wherein nIX means a whole number between 0 and 3; nix means a whole number between 1 and 3; R_TIX, R_TIX', R_TIIX and R_TIIX' are similar or different of one another and mean hydrogen atom (H) or linear or branched alkyl; Y means heterocyclic ring, saturated or unsaturated aromatic ring comprising 6 atoms and comprising one or two nitrogen atoms; R is taken among groups disclosed in the invention claim. Also, invention describes pharmaceutical compositions containing salts of above described compounds as active components and eliciting inhibitory effect on contraction of smooth muscles and cellular proliferation. Invention provides preparing new salts of compounds eliciting valuable biological properties.

EFFECT: valuable medicinal properties of compounds.

11 cl, 3 tbl, 15 ex