HYDROPYRIDINE DERIVATIVE ACID ADDITIVE SALTS Russian patent published in 2004 - IPC

Abstract RU 2238275 C1

FIELD: organic chemistry, pharmacy.

SUBSTANCE: invention relates to acid additive salts - 2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine hydrochloride and maleate. Also, invention describes a method for their preparing, medicinal agent based on salts and their using. Acid additive salts of tetrahydrothienopyridine derivatives show the excellent oral absorption, metabolism to active compound and inhibitory effect in platelet aggregation, low toxicity, excellent stability in storing and using. They can be used as therapeutic or prophylactic agents (preferably as therapeutic agents) in thrombosis and embolism.

EFFECT: valuable medicinal properties of agents.

28 cl, 4 tbl, 14 ex

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RU 2 238 275 C1

Authors

Asai Fumitosi

Ogava Taketosi

Naganuma Khideo

Jamamura Naotosi

Inoue Terukhiko

Nakamura Kazujosi

Dates

2004-10-20Published

2001-07-03Filed