FIELD: medicine, pharmacy.
SUBSTANCE: invention describes a pharmaceutical composition comprising a medicinal agent, wax-like substance and synthetic aluminum silicate and/or aqueous silicon dioxide, and oral pharmaceutical component comprising such composition. The pharmaceutical composition is prepared by granulation by spraying. Also, invention relates to an agent used for prevention in usage of granulated product to internal walls of granulator device during the granulation process by spraying. This agent represents synthetic aluminum silicate and/or aqueous silicon dioxide. Invention minimizes sticking granules in granulator device during granulation of the pharmaceutical composition and prevents caking granules.
EFFECT: improved preparing method, improved and valuable properties of composition.
13 cl, 4 tbl, 6 ex
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