FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to a solid medicinal formulation based on sulphamethoxazole and trimethoprim that represents pressed granules covered by powdering layer consisting of starch, magnesium stearate and polyplasdon. Granules comprise a mixture of indicated active substances, starch, microcrystalline cellulose and polyvinylpyrrolidone-base baking. The proposed formulation elicits the enhanced strength and improved capacity for decomposition after oral dosing.
EFFECT: improved pharmaceutical properties of formulation.
3 cl, 2 tbl, 2 ex
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