FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to derivatives of ethanesulfonylpiperidine of the formula (I):
or their pharmaceutically acceptable acid-additive salts wherein R1 means hydrogen atom or hydroxyl; R2 means hydrogen atom or methyl; X means -O- or -CH2-. Indicated compounds elicit good affinity to NMDA-receptor and can be used for treatment of diseases caused by enhanced activity of NR2B subtypes of NMDA-receptors.
EFFECT: valuable medicinal properties of compounds.
10 cl, 1 tbl, 32 ex
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