FIELD: chemistry of natural compounds, medicine.
SUBSTANCE: invention relates to the development of anticoagulant of vegetable origin. Agent eliciting anti-coagulating and immunotropic effect represents fucoidan prepared from brown alga Fucus evanescens by extraction with water at temperature 20-60oC followed by precipitation with ethanol. Fucoidan has molecular mass 20000-40000 Da and contains the following neutral monosaccharides, %: fucose, 70-80; galactose, 2-9; xylose, 5-10, and glucose, 2-7, and also sulfates, 20-22%. Fucoidan shows intensive signals in [13C]-NMR spectrum at 16.0-18.0 m.d. and the absorption band in IR-spectrum at 820-822 cm-1. Fucoidan stimulates phagocyte and bactericidal activity of neutrophiles being in the large and small doses and elicits immunostimulating effect in the broad range of doses.
EFFECT: valuable medicinal properties of agent.
2 dwg, 3 tbl
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