PRODUCT WITH ANTIAGGREGATION AND ANTICOAGULANT EFFECTS, AND METHOD OF ITS PREPARATION Russian patent published in 2023 - IPC A61K36/28 B01D11/02 A61P7/02 

FIELD: pharmaceutical industry.

SUBSTANCE: claimed invention relates to a product with antiaggregation and anticoagulant activity. A product that has an antiaggregation and anticoagulant effect, representing a dry extract obtained by extracting an analytical sample of the herb three-ribs perforatum, collected before flowering, weighing about 1.0 g of an accurate sample, crushed to the size of particles passing through a sieve with holes of 1 mm in size, in an ultrasonic cell with 50 ml of ethyl alcohol 40% with sonication for 3 minutes in a thermostatic mode at an oscillation frequency of 22 kHz and an ultrasonic power of 90 W; subsequent filtering into a 250 ml volumetric flask through a paper filter and transferring the raw material from the cell along with the filter into a 250 ml round-bottom flask connected to a reflux condenser, followed by extraction with 100 ml of 40% ethyl alcohol by heating on a hotplate with a closed spiral for 20 minutes; cooling the resulting extract, filtering into the same 250 ml volumetric flask, adjusting to the mark with 40% ethyl alcohol, followed by drying using freeze drying.

EFFECT: above-described agent has a pronounced antiaggregation and anticoagulant effect, and is characterized by an increased yield of flavonoids — 7.65±0.03% equivalent to rutin and absolutely dry raw materials.

1 cl, 2 tbl, 3 ex