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2 676 266

(13)

(51)

IPC

A61K39/12(2006-01-01)

A61K39/39(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2017120942, 2017-06-14

(24)

Start date

2017-06-14

(22)

Actual filing date

2017-06-14

(45)

Published

2018-12-27

(72)

Inventor

Kuznetsova Tatyana AlekseevnaPersiyanova Elena ViktorovnaShutikova Anna LeonidovnaBesednova Nataliya NikolaevnaErmakova Svetlana PavlovnaStepanova Lyudmila Alekseevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Institut Epidemiologii I Mikrobiologii Imeni G.P. Somova" Epidemiologii I Mikrobiologii Imeni G.P. Somova")

ADJUVANT FOR ANTI-VIRAL VACCINES Russian patent published in 2018 - IPC A61K39/12 A61K39/39 A61P31/12

Abstract RU 2676266 C2

FIELD: medicine.

SUBSTANCE: invention is intended for use in medicine, in particular in immunology, and can be used to obtain adjuvant antiviral vaccines against hepatitis B viruses or influenza. For this, fucoidan obtained from Fucus evanescens brown alga with a molecular weight of 130–430 kDa is used as an adjuvant, monosaccharide composition fucose:galactose:xylose in the ratio of 94.1:3.8:2.1 mol. %, the sulfate content of 27 %.

EFFECT: use of fucoidan with an established monosaccharide composition provides an adjuvant that enhances the immunogenicity of the hepatitis B surface antigen and influenza virus A.

1 cl, 3 tbl

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RU 2 676 266 C2

Authors

Kuznetsova Tatyana Alekseevna

Persiyanova Elena Viktorovna

Shutikova Anna Leonidovna

Besednova Nataliya Nikolaevna

Ermakova Svetlana Pavlovna

Stepanova Lyudmila Alekseevna

Dates

2018-12-27—Published

2017-06-14—Filed