FIELD: pharmaceutical industry.
SUBSTANCE: invention provides oral-administration beta-histin-based controlled-release solid preparation prepared by granulating active ingredient from melt with fat component added followed by mixing thus obtained granulate with hydrophilic polymer and conventional excipients. Invention enables preparation of pharmaceutical dosage form with appropriate beta-histin release profile allowing reduction of daily drug intake to single dose, whereas concentration of active ingredient is kept constant within therapeutical dose limits.
EFFECT: facilitated therapeutical treatment.
4 cl, 14 ex
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