FIELD: chemistry of heterocyclic compounds, antibacterial agents.
SUBSTANCE: invention relates to agent used against acid-resistant microorganisms. Invention describes agent against acid-resistant microorganisms containing as an active component the compound represented by the general formula (1) 
or its hydrate wherein R2 represents hydrogen atom; R3 represents hydrogen atom; A1, A2 and A3 form incomplete structure of the formula: 
wherein A1 represent incomplete structure of the formula: 
wherein X2 and above described R1 can be combined to form six-membered cyclic structure comprising part of the parent nucleus wherein formed ring can comprise oxygen atom and, except for, can comprise alkyl group having 1-6 carbon atoms as a substitute; X1 represents halogen atom, hydrogen atom or amino-group; Y represents hydrogen atom; Z represents incomplete structure of the formula: 
. Agent elicits high antibacterial activity of broad spectrum and possesses good pharmacokinetics and safety also.
EFFECT: improved and valuable properties of agent.
3 cl, 9 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT AGAINST ACID-RESISTANT MICROORGANISMS CONTAINING PYRIDONE CARBOXYLIC ACIDS AS ACTIVE COMPONENT | 2001 |
|
RU2299205C2 |
| DEHALOGENATED COMPOUNDS, ANTIBACTERIAL AGENT AND THERAPEUTIC AGENT BASED ON THEREOF, METHOD FOR PREPARING ANTIBACTERIAL OR MEDICINAL AGENT, USING DEHALOGENATED COMPOUNDS FOR PREPARING ANTIBACTERIAL OR MEDICINAL AGENT | 2001 |
|
RU2298006C2 |
| TRI- OR TETPA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVES | 2006 |
|
RU2420524C2 |
| CYCLOALKYL-SUBSTITUTED DERIVATIVES OF AMINOMETHYLPYRROLIDINE AND ANTIBACTERIAL AGENT BASED ON THEREOF | 1999 |
|
RU2248970C2 |
| DERIVATIVES OF AMINOMETHYLPYRROLIDINE WITH AROMATIC SUBSTITUTES | 2000 |
|
RU2255938C2 |
| AMINOQUINOLONE DERIVATIVES SUBSTITUTED BY PHENYL OR HETEROAROMATIC GROUP | 1993 |
|
RU2124510C1 |
| SPIROCOMPOUND OR SALTS THEREOF, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION BASED THEREON HAVING ANTIMICROBIAL ACTIVITY | 1989 |
|
RU2094432C1 |
| CONDENSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE | 2007 |
|
RU2443698C2 |
| BICYCLIC DERIVATIVES OF 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID OR THEIR SALTS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIBACTERIAL ACTIVITY | 1993 |
|
RU2125046C1 |
| DERIVATIVES OF PYRIMIDINE, PHARMACEUTICAL COMPOSITION, INHIBITION METHOD AND USING | 2002 |
|
RU2288227C2 |
