FIELD: medicine, in particular angiogenesis prophylaxis and treatment.
SUBSTANCE: invention relates to 2-cyclooxygenase inhibitors selected from group containing 4-[5-(4-chlorophenyl)-3-phenyl-1H-pyrazole-1-yl] benzenesulfonamide; 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl] benzenesulfonamide; 4-[5-methyl-3-phenyloxazole-4-yl] benzenesulfonamide or pharmaceutically acceptable salts thereof and pharmaceutical composition containing the same in therapeutically effective amount. Said composition are useful in treatment and/or prophylaxis of angiogenesis disorders such as metastasis, eye angiogenesis, diabetic retinopathy, etc. in subjects are needed in such treatment and/or prophylaxis.
EFFECT: new pharmaceuticals for angiogenesis treatment and/or prophylaxis.
5 cl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR APPLYING CYCLOOXYGENASE-2 INHIBITOR FOR TREATMENT AND PROPHYLAXIS OF NEOPLASIA | 1997 |
|
RU2239429C2 |
| PHARMACEUTICAL COMPOSITION FOR USING IN THERAPY OF MALIGNANT NEOPLASM COMPRISING COMBINATION OF BISPHOSPHONATE, COX-2 INHIBITOR AND TAXOL | 2002 |
|
RU2317819C2 |
| METHOD FOR TREATING INFLAMMATION OR INFLAMMATION-INDUCED DISEASE IN DOGS | 1996 |
|
RU2253456C2 |
| PYRAZOLYL-SUBSTITUTED BENZENESULFONEAMIDE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF TREATMENT OF PATIENTS WITH INFLAMMATION OR INFLAMMATION-ASSOCIATED DISEASES | 1994 |
|
RU2139281C1 |
| METHOD OF PREPARING 3-HALOGENALKYL-1H- PYRAZOLES | 1996 |
|
RU2169143C2 |
| 3-(5)-HETEROARYL-SUBSTITUTED PYRAZOLES AS KINASE P38 INHIBITORS | 1998 |
|
RU2249591C2 |
| DIKETONE AS INTERMEDIATE FOR 3-HALOGENE-1H-PYRASOLES | 1996 |
|
RU2251543C2 |
| SUBSTITUTED ISOXAZOLES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF INFLAMMATION SUPPRESSION | 1996 |
|
RU2200158C2 |
| COMBINATIONS CONTAININS Bcr-Abl/c-Kit/PDGF-RTK INHIBITORS FOR TREATING CANCER | 2007 |
|
RU2452492C2 |
| SYNTHESIS OF DIARYLPYRAZOLES | 2003 |
|
RU2319695C2 |
