METHOD AND DEVICE FOR REGISTERING BIOLOGICAL, CHEMICAL AND BIOCHEMICAL PROCESSES AT LIQUID-SOLID BODY BOUNDARY Russian patent published in 2005 - IPC

FIELD: chemical industry; biological industry.

SUBSTANCE: method and device can be used for testing biological, chemical and biochemical surface sensors which operation is based upon excitation of surface electromagnetic waves on surface of solid body. Change in phase of surface (or waveguide) wave is measured by means of interference between signal wave (waveguide or plasma) propagating along tested surface and volumetric reference wave propagating inside liquid directly above the surface at a small angle to the surface. Both interfering waves pass through liquid cell. One wave has shape of surface (plasma or waveguide) wave, the other one has shape of volumetric wave propagating directly above the surface. Change in volumetric parameters of liquid, for example, refractivity, influences both waves - signal surface and reference volumetric. The influence is mutually compensated in registered interference signal. Sensitivity to volumetric parameters of liquid is reduced while high sensitivity to properties of surface layer is kept.

EFFECT: improved precision.

7 cl, 10 dwg