METHOD FOR EVALUATING THE ACTION AND EFFICIENCY OF ANTIMICROBIAL PREPARATIONS UPON ORAL MICROFLORA Russian patent published in 2005 - IPC

FIELD: medicine.

SUBSTANCE: the present innovation deals with comparing the amplitudes of test curves of pH measurement in mouth cavitary media both before and after application of suggested preparations. Test curves of pH measurement towards acidic side are being obtained after activating acid-forming oral microflora with 15 ml 50%-saccharose solution as oral rinsing for 30 sec, and test curves of pH measurement towards alkaline side are being obtained after activating ammonia-forming microflora with 15 ml 8%-carbamide solution (oral rinsing for 30 sec). One should evaluate the efficiency of such preparations according to the difference of amplitudes for test saccharose and carbamide pH curves (ΔAs and ΔAc) obtained both before and after application of the preparations suggested, total evaluation of preparation impact upon oral microflora should be performed due to comparing the values of ΔAs and ΔAc. The method provides evaluation of preparation impact not only upon acid-producing oral microflora but ammonia-producing one, as well.

EFFECT: higher efficiency and accuracy of evaluation.

1 dwg, 1 ex