METHOD OF INDIVIDUAL ESTIMATION OF SENSITIVITY OF MOUTH MICROFLORA TO ANTIMICROBIAL AGENTS Russian patent published in 2007 - IPC G01N33/84 

FIELD: stomatology.

SUBSTANCE: one compares amplitudes of test sugar (A_c) and urea (A_k) before and after use of antimicrobial agent (ΔA_s=A₁₀-A_2s and ΔA_u=A_1u-A_2u)_. Test sugar pH curves are obtained by stimulating acid-producing mouth cavity microflora with 47% saccharose solution and urea _{pH curves are obtained by stimulating ammonia-producing microflora with 8% urea solution. Individual feature of sensitivity of mouth microflora to antimicrobial agents associated with its qualitative composition is determined from asymmetry coefficient obtained from formula: Ka = ΔAu/ΔAs and individual feature associated with its quantitative composition is determined from coefficient of prevailing effect obtained from formula: Kpe = [(A1u+A1s)/2]/[(A2u+A2s)/2]. Coefficient values are then compared with reference values obtained from reference group and individual sensitivities of mouth microflora to antimicrobial agents are estimated as difference of these values.}

EFFECT: accelerated estimation and enabled differentiation of estimation according to qualitative and quantitative characteristics.

1 dwg