APPLYING ANTAGONIST OF CENTRAL CANNABINOID RECEPTOR FOR PREPARING DRUGS DESIGNATED FOR RELIEF IN SMOKING CEASING Russian patent published in 2005 - IPC

Abstract RU 2257207 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention proposes applying N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazol-3-carboxamide or its salt for manufacturing a medicinal agent used for treatment of nicotine dependence and/or symptoms of nicotine withdrawal syndrome and a method for help in ceasing using tobacco. The claimed compound is known as antagonist of central cannabinoid receptors and agent used for treatment of disorders associated with using psychoactive substances. Indicated compounds are effective with respect to complete or partial tobacco abstinence with elimination of attenuation of nicotine withdrawal syndrome and patients show reduced weight loss or its absence.

EFFECT: valuable medicinal properties of antagonist.

3 cl, 5 ex

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RU 2 257 207 C2

Authors

Blanshar Zhan Sharl'

Menar Fransua

Dates

2005-07-27—Published

2001-02-07—Filed