FIELD: pharmacology.
SUBSTANCE: present invention concerns compounds of formula I where R1 represents group R5S(O)2O wherein R5 represents group C1-10alkyl optionally substituted with one or more fluoro; R2a and R2b represent H or chloro; R3 represents group CONHNR7R8 wherein NR7R8 represents pyperidine-1-yl; and R4 represents group C1-3alkyl, and its pharmaceutically acceptable salts. Besides the invention concerns a pharmaceutical composition based on the compound of formula I and to application thereof in manufacturing of medicines possessing activity to CB1 receptor.
EFFECT: new imidazole derivatives expressing effective biological properties.
16 cl, 14 ex
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Authors
Dates
2009-12-27—Published
2005-03-30—Filed