XENON AS N-METHYL-D-ASPARTIC ACID ANTAGONIST Russian patent published in 2005 - IPC

Abstract RU 2257902 C2

FIELD: neurology.

SUBSTANCE: invention proposes: use of xenon being N-methyl-D-aspartic acid antagonist in function of neuroprotector and/or synaptic activity inhibitor, a method ensuring neuroprotection and/or synaptic activity inhibition, a method of preparing pharmaceutical composition and a pharmaceutical composition with indicated destination, and use of xenon to prepare pharmaceutical agent for neuroprotection and/or synaptic activity inhibition. Invention is distinguished by revealed possibility for known N-methyl-D-aspartic acid antagonist to decrease, by more than 30%, glutamate-caused damage of neurons and glia cells. In case of prolonged action of xenon, indicated damage can be additionally decreased by more than 55%.

EFFECT: expanded possibilities in neuroprotection field.

14 cl, 15 dwg, 2 tbl

Similar patents RU2257902C2

Title Year Author Number
ANESTHETIC COMPOSITION COMPRISING NMDA-ANTAGONIST AND ALPHA-2-ADRENERGIC AGONIST 2000
  • Frehnks Nikolas Piter
  • Mehjz Mervin
RU2244558C2
COMPOUNDS BEING ACTIVE AT A NEW SITE UPON RECEPTOR-OPERATED CALCIUM CANALS APPLIED FOR TREATING NEUROLOGICAL DISORDERS 1996
  • Alan L. Mjuller
  • Skott T. Moeh
  • Manuehl F. Balandrin
  • Ehrik Dzh. Delmar
  • Bredford K. Vanvagenen
  • Linda D. Artman
  • Robert M. Barmor
  • Dehril L. Smit
RU2246300C2
COMBINED DRUG FOR PRIMARY NEUROPROTECTION 2017
  • Kucherenko Lyudmila Ivanovna
  • Khromyleva Olga Vladimirovna
  • Mazur Ivan Antonovich
  • Belenichev Igor Fedorovich
  • Gorbacheva Svetlana Vasilevna
RU2636616C1
MODULATOR OF NMDA-RECEPTOR WITH STABILISED SECONDARY STRUCTURE AND ITS USAGE 2011
  • Moskal Dzhozef
  • Kkhan Amin
RU2566821C2
DERIVATIVES OF 5B-SAPOGENIN AND PSEUDO SAPOGENIN AND APPLICATION FOR DEMENTIA MEDICAL TREATMENT 2000
  • Barraklu Pol
  • Khehnson Dzhim
  • Ganning Fil
  • Riz Dehril
  • Ksia Zongkin
  • Khu Jaehr
RU2325396C2
COMBINATIONS OF COMPOUNDS MODULATING THE NMDA RECEPTOR 2015
  • Moskal Dzhozef R.
RU2721948C2
PHARMACEUTICAL COMPOSITION FOR USE IN TREATMENT OF NEURODEGENERATIVE DISEASE 2012
  • Khess Zibille
  • Khelsher Kristian
  • Beme Andres
  • Menyu Agnes
  • Prade Loran
  • Topen Veronik
RU2618412C2
THERAPEUTIC TREATMENT OF METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY OR POTENTIAL DIABETES 2008
  • Kinkotta Ehntoni Kh.
RU2467743C2
CYCLOPROPYLPIPERIDINE GLYCINE TRANSPORTER INHIBITORS 2005
  • Lindsli Krejg U.
  • Uisnoski Dehvid D.
  • Uolkenberg Skott Eh.
RU2387644C2
CB1 RECEPTOR ANTAGONISTS 2012
  • Pyatstsa Per Vinchentso
  • Valle Monik
  • Marsikano Dzhovanni
  • Felpen Fransua-Ksave
  • Bellokko Luidzhi
  • Kota Daniela
  • Revest Zhan-Mishel
  • Vitello Serdzho
  • Spampinato Umberto
  • Maldonado Rafael
RU2593751C2

RU 2 257 902 C2

Authors

Frehnks Nikolas Piter

Mehjz Mervin

Dates

2005-08-10Published

2000-07-28Filed