COMBINATIONS OF COMPOUNDS MODULATING THE NMDA RECEPTOR Russian patent published in 2020 - IPC A61K38/07 A61P25/00 

Abstract RU 2721948 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a method for reverse development or prevention of cognitive impairment in a patient to whom an NMDA receptor antagonist is introduced, comprising administering an effective amount of GLYX-13, wherein the NMDA receptor antagonist is ketamine or phencyclidine. Invention also relates to a method of treating a neurological disorder or stroke, psychosis, pain, depression, Parkinson's disease, Alzheimer's disease, a method of treating a central nervous system disease, a method of treating schizophrenia, a method of treating depression, a pharmaceutically acceptable composition.

EFFECT: use of the present invention enables neutralizing a side effect of the NMDA receptor antagonist.

25 cl, 6 dwg

Similar patents RU2721948C2

Title Year Author Number
PHARMACEUTICAL COMBINATION OF ATYPICAL ANTIPSYCHOTIC AND NMDA MODULATOR FOR TREATMENT OF SCHIZOPHRENIA, BIPOLAR DISORDER, COGNITIVE DISORDER, AND CLINICAL DEPRESSION 2016
  • Moskal Joseph R.
  • Meltzer Hebert
RU2802972C2
CYCLOPROPYLPIPERIDINE GLYCINE TRANSPORTER INHIBITORS 2005
  • Lindsli Krejg U.
  • Uisnoski Dehvid D.
  • Uolkenberg Skott Eh.
RU2387644C2
METHODS OF TREATING OR RELIEVING MIGRAINE 2015
  • Moskal Dzhozef R.
  • Stenton Patrik
RU2721401C2
STABLE COMPOSITIONS OF NEUROACTIVE PEPTIDES 2015
  • Khouk Devid Renvik
  • Argavani Mosen
RU2716164C2
MEDICINAL AGENTS USED FOR PROPHYLAXIS AND TREATMENT OF NEURODEGENERATIVE DISEASES 2001
  • Furukava Kiesi
  • Kurumija Satosi
  • Okimoto Kazuo
  • Okhno Kazunori
RU2258506C2
MODULATOR OF NMDA-RECEPTOR WITH STABILISED SECONDARY STRUCTURE AND ITS USAGE 2011
  • Moskal Dzhozef
  • Kkhan Amin
RU2566821C2
METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA WITH USING NEUROLEPTIC COMBINED THERAPY 2007
  • Bachurin Sergej Olegovich
  • Grigor'Ev Vladimir Viktorovich
  • Morozova Margarita Alekseevna
  • Beniashvili Allan Gerovich
RU2508096C2
METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA WITH USING ATYPICAL NEUROLEPTIC COMBINED THERAPY 2007
  • Bachurin Sergej Olegovich
  • Grigor'Ev Vladimir Viktorovich
  • Morozova Margarita Alekseevna
  • Beniashvili Allan Gerovich
RU2508106C2
PEPTIDE ANTAGONIST OF THE NMDA RECEPTOR 2019
  • Karlov Dmitry Sergeevich
  • Fedorov Maxim Valerevich
  • Paliulin Vladimir Aleksandrovich
  • Grigorev Vladimir Viktorovich
RU2716258C1
THERAPEUTIC APPLICATION OF SELECTIVE INHIBITORS PDE10 2003
  • Lebel Lorrejn Ehnn
  • Menniti Frank Sehm'Juehl'
  • Shmidt Kristofer Dzhozef
RU2303259C2

RU 2 721 948 C2

Authors

Moskal Dzhozef R.

Dates

2020-05-25Published

2015-05-06Filed