FIELD: biology, biochemistry, science-practical pharmacology, molecular biology.
SUBSTANCE: invention relates to isolated DNA fragment with indicated nucleotide sequence encoding protein that elicits property of intramembrane endoprotease (IMPAS), and to a method for preparing this protein. Invention provides the possibility for development of preparations used for diagnosis of diseases associated with proteolysis of intracellular receptors. Invention provides expanding assortment of agents useful in treatment of different neurological, cardiovascular and other diseases associated with the disturbed proteolysis of proteins.
EFFECT: improved preparing method, valuable medicinal properties of protein.
3 cl, 4 dwg, 1 tbl, 3 ex
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