FIELD: medicine, oncology.
SUBSTANCE: invention relates to a method for treatment of patients with disseminated forms of prostate cancer. Method involves administration of navelbine in the dose 30 mg/m2 on the background of anti-androgenic therapy. The course time in navelbine administration is 4 weeks and from 7-th day after the last injection of navelbine method involves administration of strontium-89 chloride in the dose 4 mKi (150 MBk), once time per 3 months, two injections. For patients with the amount of osseous metastases above 6 the dose of strontium-89 chloride is 8 mKi per one administration (300 MBk). In further courses of systemic therapy are repeated in 3 months, not early. Method shows the optimal regimen set in administration of preparations and provides the maximal effect of navelbine on osseous metastases followed by damaging effect of strontium-89 chloride on blood vessels of tumor and its cells and the absence of the potentiation toxicity on the hemopoiesis system.
EFFECT: improved and enhanced effectiveness of treatment.
3 dwg, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR TREATING LOCAL HORMONE-RESISTANT FORMS OF PROSTATIC CANCER | 2002 |
|
RU2229880C2 |
METHOD FOR TREATING LOCALLY METASTASING FORMS BLADDER'S CANCER | 2004 |
|
RU2260434C1 |
METHOD FOR TREATMENT OF PLURAL OSTEAL METASTASISES DURING MAMMARY GLAND CANCER | 2007 |
|
RU2332992C1 |
METHOD OF TREATMENT OF PATIENT WITH OSTEOLYTIC METASTASIS | 1999 |
|
RU2153358C1 |
METHOD OF TREATING PATIENTS WITH METASTASES IN LYMPH NODES AND OLIGOMETASTATIC DISEASE IN BONES OF SKELETON IN PROSTATE CANCER | 2018 |
|
RU2695348C2 |
METHOD FOR THE TREATMENT OF PRIMARY METASTATIC PROSTATE CANCER | 2022 |
|
RU2796395C1 |
METHOD FOR VERIFICATION OF DOSE DURING MEDICAL ADMINISTRATION OF OPEN RADIOACTIVE NUCLIDES | 2005 |
|
RU2289458C2 |
METHOD OF TREATING SPINE TUMOURS | 2014 |
|
RU2551622C1 |
METHOD FOR EVALUATING THE BONE SCINTIGRAPHY RESULTS IN PATIENTS WITH METASTATIC LESIONS OF THE SKELETON BONES | 2022 |
|
RU2791402C1 |
METHOD OF TREATING METASTASES OF STOMACH CANCER IN BONES | 2023 |
|
RU2810137C1 |
Authors
Dates
2005-09-20—Published
2004-03-18—Filed