FIELD: medicine, oncology.
SUBSTANCE: the present innovation deals with treating locally metastasing forms of bladder's cancer at T2b-4N0-1M0 stages. It deals with performing chemotherapy due to fractional introduction of total therapeutic dosage of cytostatic preparation into pubic bone - adriamycin at a single dosage being not more than 30 mg every other day per one course up to total dosage of 70 mg/m2. After each injection one should introduce per 2 ml 2%-lidocaine solution through the same needle. For patients with contra-indications for systemic chemotherapy total adriamycin dosage should be decreased twice to be distributed for three injections. The method increases adriamycin concentration in tumor at optimal way and mode of its injection by providing decreased number of toxic complications, in patients above 75 or with severe accompanied pathology, among them.
EFFECT: higher efficiency of therapy.
2 ex
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Authors
Dates
2005-09-20—Published
2004-03-18—Filed