FIELD: biochemistry, medicine.
SUBSTANCE: invention relates to two forms of peptide isolated from annelid worm (Arenicola marina) eliciting the broad spectrum of antibacterial effect. Indicated forms differ by a single amino acid residue at position 10 wherein at position 10 arenicin-1 has Val and arenicin-2 has Ile. Invention provides expanding assortment of antibacterial agents.
EFFECT: valuable medicinal properties of peptides.
1 tbl, 3 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING ANTIMICROBIAL PEPTIDE ARENICIN | 2006 |
|
RU2316595C1 |
| BETA-HAIRPIN PEPTIDE WITH ANTIMICROBIAL ACTIVITY AGAINST MULTIDRUG-RESISTANT BACTERIA | 2023 |
|
RU2812977C1 |
| RECOMBINANT PLASMID DNA pE-His8-TrxL-Ar2 ENCODING FUSION PROTEIN COMPRISING ANTIMICROBIAL SEA ANNELID WORM Arenicola marina PEPTIDE ARENICIN AND STRAIN Escherichia coli BL21(DE3)/pE-His8-TrxL-Ar2 AS PRODUCER OF ARENICIN-CONTAINING FUSION PROTEIN | 2006 |
|
RU2316590C1 |
| NIKOMYCIN PEPTIDE FROM NEREID NICOMACHE MINOR POSSESSING ANTIMICROBIAL AND ANTITUMOUR ACTIVITY | 2019 |
|
RU2721273C1 |
| BETA-HAIRPIN POLYPEPTIDE WITH ANTIMICROBIAL ACTIVITY | 2015 |
|
RU2624020C2 |
| LATARCIN PEPTIDES HAVING ANTIBACTERIAL ACTIVITY | 2005 |
|
RU2302466C1 |
| RECOMBINANT PLASMID DNA pЕ-Trx-Lc-def, Escherichia coli STRAIN FOR EXPRESSION OF ANTIMICROBIAL PEPTIDE OF LENTIL DEFENSIN Lens culinaris AND METHOD FOR PRODUCING SAID PEPTIDE | 2010 |
|
RU2456345C1 |
| PEPTIDES EXHIBITING ANTIMICROBIAL ACTIVITY | 2005 |
|
RU2302425C2 |
| RECOMBINANT PLASMID DNA pET-KSI-Buf2, CODING HYBRID PROTEIN, CONTAINING ANTIMICROBIAL PEPTIDE BUFORIN-2, STRAIN OF Escherichia coli BL21(DE3)/pET-KSI-Buf2-PRODUCER OF INDICATED PROTEIN AND METHOD OF OBTAINING ANTIMICROBIAL PEPTIDE BUFORIN-2 | 2007 |
|
RU2347811C1 |
| PLASMID VECTOR pE-Trx-Aur, STRAIN ESCHERICHIA COLI FOR EXPRESSION OF ANTIMICROBIAL PEPTIDE AURELIN AND METHOD OF SAID PEPTIDE OBTAINING | 2009 |
|
RU2412999C1 |
