METHOD FOR PREDICTING RESULTS OF TRANSITORY SYNOVITIS OF HIP JOINT IN CHILDREN Russian patent published in 2005 - IPC

FIELD: medicine, arthrology.

SUBSTANCE: one should detect antigens of the main complex of histocompatibility (HLA) and immune values: blast-transformation reaction (BTR) and nitroblue tetrazolium test (NBT). At detecting HLA A1 or HLA B27 at simultaneous BTR decrease <50% and NBT-test <0.2 conventional units in acute period one should predict the result of transitory synovitis of hip joint into Perthes disease (PD). In case of detecting HLA B7 at physiological values of BTR being 50%-80% and NBT-test being 0.2-0.4 conventional units the result should be -patient's recovery. The innovation enables to predict the flow of transitory synovitis of hip joint in children at the earliest, initial stages of the disease that gives the chance to detect the risk group and carry out advancing pathogenetic therapy in patients with transitory synovitis to improve circulation in caput femoris with the purpose to prevent the development of aseptic necrosis of caput femoris, that is PB mentioned above.

EFFECT: higher accuracy of prediction.

2 dwg, 3 ex, 3 tbl