DERIVATIVES OF 8,8A-DIHYDROINDENO[1,2-D]THIAZOLE COMPRISING SUBSTITUTE WITH SULFONAMIDE OR SULFONE STRUCTURE AT POSITION 2, METHOD FOR THEIR PREPARING AND THEIR APPLYING AS MEDICINAL AGENT Russian patent published in 2005 - IPC

FIELD: organic chemistry, chemical technology, medicine.

SUBSTANCE: invention relates to polycyclic dihydrothiazole and to their physiologically acceptable salts and physiologically functional derivatives. Invention describes compounds of the formula (I): wherein R1 and R1' mean independently of one another atoms of hydrogen (H), fluorine (F), chlorine (Cl), bromine (Br) and iodine (J); R2 and R3 mean hydrogen atom (H); R4 means (CH₂)_n-R5 wherein n can be = 0-6; R5 means phenyl that can be substituted with NH-SO₂-(C₁-C₆)-alkyl, NH-SO₂-phenyl being phenyl ring up to twice-fold can be substituted with chlorine atom (Cl), (CH₂)_m-SO₂-NH₂, (CH₂)-SO₂-NH-(C₁-C₆)-alkyl, (CH₂)_m-SO₂-N-[(C₁-C₆)-alkyl]₂ or (CH₂)_m-SO₂-N-[=CH-N(CH₃)₂] wherein m can be = 0-6, and a method for their preparing. Compounds are useful, for example, as anorexic agents used in prophylaxis or treatment of obesity.

EFFECT: improved preparing method, valuable medicinal properties of compounds.

5 cl, 12 tbl, 2 ex