FIELD: chemistry.
SUBSTANCE: invention relates to cytotoxic compounds with directional effect, which are peptide derivatives of camtothecin, doxyrubicin and palitaxel, their pharmaceutical compositions and use in making medicinal agents for treating pathological conditions, related to aberrant or undesirable proliferation, migration and/or physiological activity of cells.
EFFECT: agents are highly effective.
43 cl, 79 ex, 1 tbl
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| CONJUGATES OF CYTOTOXIC AGENTS WITH PEPTIDES | 2007 |
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| CHIMERIC ANALOGS OF SOMATOSTATIN-DOPAMINE | 2002 |
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| CHIMERIC EQUIVALENTS OF LIGANS OF SOMATOSTATIN AND DOPERMINE RECEPTORS, PHARMACEUTICAL COMPOSITIONS BASED ON THEM AND MODALTIES OF SOMATOSTATIN AND/DOPERMINE RECEPTORS | 2004 |
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| PHARMACEUTICAL COMPOSITIONS OF SOMATOSTATIN-DOPAMINE CONJUGATES | 2009 |
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| GLP-1 PEPTIDE HAVING ATTACHED OLIGOSACCHARIDE CHAIN | 2008 |
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| GLYCATED PEPTIDE GLP-1 | 2009 |
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RU2543157C2 |
| NEUROMEDIN AND SOMATOSTATIN RECEPTOR AGONISTS | 2000 |
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| PROCESS FOR PREPARATION OF GLYCOPEPTIDE HAVING SIALYLATED SUGAR CHAIN, AND METHOD FOR PRODUCING SIALYL GLYCOASPARAGINE | 2012 |
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| PEPTIDIC INTERLEUKIN-23 RECEPTOR INHIBITORS FOR ORAL ADMINISTRATION AND USE THEREOF FOR TREATING INFLAMMATORY INTESTINAL DISEASES | 2015 |
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| SOMATOSTATIN RECEPTOR ANTAGONISTS | 1997 |
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