FIELD: organic chemistry, biochemistry, medicine, pharmacy.
SUBSTANCE: invention relates to a pharmaceutical composition comprising (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-methyl-[(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid as an active component or its pharmaceutically acceptable salt and inorganic salt with polyvalent cation also. Also, invention proposes a method for preparing the stabilized pharmaceutical composition. Invention provides preparing the stabilized pharmaceutical composition.
EFFECT: valuable medicinal properties of composition.
25 cl, 4 ex
Title |
Year |
Author |
Number |
PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITOR OF HMG-REDUCTASE |
2000 |
- Krikmor Dzhozef Richard
- Uigginz Norman Al'Fred
|
RU2206324C1 |
APPLICATION OF 3-HYDROXY-3-METHTYLGLUTARYL-COENZYME A REDUCTASE INHIBITORS IN PRODUCING MEDICINAL AGENT FOR TREATMENT OF DIABETIC NEUROPATHY |
2000 |
- Kehmeron Norman Judzhin
- Kotter Mehri Ehnn
|
RU2239456C2 |
HYPOLIPIDEMIC DOSAGE FORM AND METHOD FOR PREPARING IT |
2013 |
- Aleksenko Pavel Vladimirovich
|
RU2547574C2 |
PHARMACEUTICAL COMPOSITION CONTAINING ROSUVASTATIN CALCIUM SALT (VERSIONS) |
2015 |
- Khannanov Timur Shamilovich
- Anisimov Aleksandr Nikolaevich
- Filippov Yurij Valerevich
- Khamidullin Rustem Tafkilevich
- Gazizova Nailya Ganievna
- Ganeeva Gulnaz Shamilevna
|
RU2606592C1 |
CRYSTALLINE FORM OF CALCIUM SALT OF BIS-[(E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULPHONYL)AMINO]-PYRIMIDIN-5-YL](3R, 5S)-3, 5-DIHYDROXYHEPT-6-ENOIC ACID |
2004 |
- But Rebekka Dzhejn
- Sittern Piter Ehntoni
- Krabb Dzheffri Norman
- Khorberi Dzhon
- Dzhouns Dejvid Uin Kalvert
|
RU2363697C2 |
7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2- [METHYL(METHYLSULFONYL)AMINO]PYRIMIDIN -5-YL]-(3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID CRYSTALLINE SALTS, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION |
2001 |
- Tehjlor Najdzhel Filip
- Okada Tetsuo
|
RU2265599C2 |
METHOD OF ROSUVASTATIN CALCIUM SALT PREPARATION |
2003 |
- Khorberi Dzhon
- Tejlor Najdzhel Filip
|
RU2326871C2 |
CRYSTALLINE HYDRATED FORM OF BIS-[(E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO]-PYRIMIDINE-5-YL]-(3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID] CALCIUM SALT, METHOD FOR ITS PREPARING, PHARMACEUTICAL COMPOSITION, METHOD FOR ITS PREPARING AND METHOD FOR TREATMENT |
1999 |
|
RU2236404C2 |
METHOD OF PRODUCING ROSUVASTATIN CALCIUM SALT (E) -7-[4-(4-FLUOROPHEHYL)-6-ISOPROPYL-2-[METHYL(METHYLSULPHONYL)AMINO]PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATE PRODUCTS THEREOF |
2004 |
- Okada Tetsuo
- Khorberi Dzhon
- Laffan Dejvid Dermot Patrik
|
RU2372349C2 |
PHARMACEUTICAL COMPOSITION |
1992 |
- Mokhan Balakhandra Kabadi
- Richard Viktor Vivilechchia
|
RU2121835C1 |