UREA-SUBSTITUTED IMIDAZOQUINOLINES, PHARMACEUTICAL PREPARATION AND METHOD FOR INDUCTION OF CYTOKINE BIOSYNTHESIS BASED ON THEREOF Russian patent published in 2005 - IPC

Abstract RU 2265020 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to new urea-substituted imidazoquinolines of the formula (1):

wherein R, R1, R2 and n have values given in the description, and to pharmaceutical preparations based on these compounds. Proposed compounds possess effect of immunomodulators initiating biosynthesis of different cytokines. Also, invention relates to methods for treatment of different states, among them viral diseases and neoplastic pathologies.

EFFECT: improved method for induction, valuable properties of compounds.

47 cl, 11 tbl, 142 ex

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RU 2 265 020 C2

Authors

Kruks Stefen L.

Merrill Brajon A.

Rajs Majkl Dzh.

Dates

2005-11-27Published

2000-06-08Filed