FIELD: organic chemistry, medicine, oncology, pharmacy.
SUBSTANCE: invention relates to a novel synthesis of compound of the formula (5) 
representing a key intermediate compound in synthesis of strong anti-tumor agent ectenascidine 743 of the formula (1) 
and phthalascidine of the formula (2) 
and easily available intermediate compounds of formulae (3) 
and (4) 
. Invention provides simplifying process.
EFFECT: improved method for synthesis.
26 cl, 16 ex
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