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2 274 642

(13)

(51)

IPC

C07K5/23(2006-01-01)

A61K38/04(2006-01-01)

A61P37/00(2006-01-01)

(21) (22)

Application

2000126298/04, 1999-03-19

(24)

Start date

1999-03-19

(22)

Actual filing date

1999-03-19

(45)

Published

2006-04-20

(72)

Inventor

Vannamehjker Marion V.Bemis Gaj V.Charifson Pol S.Loffer Dehvid Dzh.Mallikan Majkl D.Merko Mark A.Vilson Kejt P.Dzhanetka Dzhehjms V.Dehvis Robert Dzh.Grilo Ann-LorShi ZanForster Kornelia Dzh.

(73)

Holder

Verteks Farmas'Jutikalz Inkorporejted

CASPASE INHIBITORS Russian patent published in 2006 - IPC C07K5/23 A61K38/04 A61P37/00

Abstract RU 2274642 C2

FIELD: medicine, biochemistry, pharmacy.

SUBSTANCE: invention relates to new compounds that represent inhibitors of caspases, in particular, inhibitors of interleukin-1β-converting enzyme and their pharmaceutical compositions. Proposed compounds can be used successfully as agents directed against diseases mediated by interleukin-1, apoptosis and factor inducing interferon-γ or by interferon-γ.

EFFECT: valuable medicinal and biochemical inhibitors.

35 cl

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RU 2 274 642 C2

Authors

Vannamehjker Marion V.

Bemis Gaj V.

Charifson Pol S.

Loffer Dehvid Dzh.

Mallikan Majkl D.

Merko Mark A.

Vilson Kejt P.

Dzhanetka Dzhehjms V.

Dehvis Robert Dzh.

Grilo Ann-Lor

Shi Zan

Forster Kornelia Dzh.

Dates

2006-04-20—Published

1999-03-19—Filed