FIELD: medicine.
SUBSTANCE: binding structure is to be bound in tumor cells and/or to tumor cell surface. Target structure available and/or expressing in the tumor cells and/or on tumor cell surface. The binding structure recognizes and blocks the target structure. Substance binding to the target structure or blocks the target structure expression is described. Pharmaceutical compositions comprise the binding structure, target structure or the substance as active principle. Methods for making phage selection, and methods for making in-vitro and in vivo diagnosis and prognosis and methods for treating malignant human diseases provide for the materials usage.
EFFECT: enhanced effectiveness in treating tumor diseases.
42 cl, 14 dwg, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODY RAISED AGAINST TO HUMAN GASTROENTERIC TRACT EPITHELIAL TUMOR ANTIGEN RELATED WITH ALPHA-6,BETA-4-INTEGRIN | 2000 |
|
RU2266298C2 |
| CONJUGATE ELICITING ABILITY TO ACTIVATE IMMUNE SYSTEM AND PHARMACEUTICAL COMPOSITION COMPRISING INDICATED CONJUGATE | 1997 |
|
RU2198895C2 |
| CONJUGATE TO STIMULATE IMMUNE RESPONSE AGAINST A TARGET CELL, METHOD TO TREAT MALIGNANT TUMORS IN MAMMALIANS | 1995 |
|
RU2183215C2 |
| BIOLOGICAL MATERIALS AND APPLICATION THEREOF | 2006 |
|
RU2432363C9 |
| INHIBITION OF TUMOUR METASTASES BY ANTIBODIES AGAINST NEUROPILINE-2 | 2007 |
|
RU2437677C2 |
| SELECTIVE BIFUNCTIONAL DRUG ON THE BASIS OF FRAGMENTS OF CAMEL SINGLE-CHAIN ANTIBODIES, AIMED ON TUMOR RECEPTORS CD47/CD44, INTENDED FOR THERAPY OF MALIGNANT NEOPLASMS | 2016 |
|
RU2658764C1 |
| ANTIBODIES AGAINST CCR7 RECEPTOR FOR CANCER TREATMENT | 2006 |
|
RU2404808C2 |
| METHOD OF SCREENING PHAGE DISPLAY LIBRARY | 2005 |
|
RU2402777C2 |
| DIRECT IMMUNOHISTOCHEMICAL ANALYSIS | 2015 |
|
RU2744836C2 |
| ANTIBODIES RECOGNISING CARBOHYDRATE CONTAINING EPITOPE ON CD-43 AND CEA EXPRESSED ON CANCER CELLS, AND METHODS OF USING SUCH | 2007 |
|
RU2461572C2 |
