METHOD OF PULSE-MEASURING EVALUATION OF FUNCTIONAL CONDITION AND CHARACTER OF VEGETATIVE REGULATION OF HUMAN CARDIO-VASCULAR SYSTEM Russian patent published in 2006 - IPC A61B5/205 A61B5/452 

FIELD: medicine; cardiology.

SUBSTANCE: method allows registering differential sphygmograms by means of computer and piezoelectric transducer providing high precision. Registration is carried out continuously and doesn't take much labor input. On the base of sphygmograms by using method of finding of "coding" points, two main characteristics of heart beat rate can be found by express analysis. Two main characteristics have to be rhythm and pulse oscillations of arterial pressure induced by periodical throwing of shock volume of blood into aorta. Algorithm of data processing which is developed on purpose, provides automatic placing of "coding" (received on the base of calculation) points onto averaged graph of cardiologic cycle that provides higher precision of determination of amplitude-time parameters at any recognized normal pulsation of selected fragment of pulsogram together with additional visual correction of localization of those points. Fragment of pulsogram with duration of no less than 2 minutes (standard duration equals to 5 minutes) is used for measuring and analyzing time factors which characterize rhythm of heart beating and its variability. After that the calibration factor is calculated to transfer conditional units of computer "digitization" into common units of measurement of blood arterial pressure (in mm of mercury column) and values of pulsation increase in blood arterial pressure in mm of mercury column are determined by integrating cardiologic cycles at selected fragment of pulsogram for corresponding areas. The meanings achieved are used for calculating all the amplitude-time cardiologic hemo-dynamic factors which depend on blood arterial pressure and which characterize systole of myocardium of left ventricle and elastic-resilient properties of walls of arterial channel. Continuous monitoring of changes in amplitude-time factors of pulsogram is provided as well as practically real time scale of getting of all the computational data and quick performance of all the mathematical transformations for making spectral analysis of variability of heart beat rate and selected amplitude-time cardiologic hemo-dynamic factors to determine their total and differential spectral power of oscillations. Results of static and spectral analysis of variability of measured parameters the functional condition and character of vegetative regulation of cardio-vascular system are estimated due to comparison of measured values with average statistical numerical values of the same factors which were specified for cardio-vascular system in relation to age, sex, state of health and signs for groups of people chosen as a test group.

EFFECT: improved precision; widened number of informative factors for estimation of cardio-vascular system.

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