PHARMACEUTICAL COMPOSITION FOR USING IN THERAPY OF MALIGNANT NEOPLASM COMPRISING COMBINATION OF BISPHOSPHONATE, COX-2 INHIBITOR AND TAXOL Russian patent published in 2008 - IPC A61K31/663 A61K31/337 A61P35/00 A61K31/341 A61K31/196 A61K31/222 A61K31/415 

Abstract RU 2317819 C2

FIELD: medicine, oncology, pharmacy.

SUBSTANCE: invention relates to drugs, in particular, to a pharmaceutical composition used in treatment of breast cancer. Pharmaceutical composition comprises bisphosphonate, COX-2 inhibitor and taxotere for simultaneous, successive or separate using wherein bisphosphonate represents 2-(imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic acid (zolendronic acid) or its pharmacologically acceptable salt and wherein compound SC236 represents inhibitor of COX-2.

EFFECT: valuable medicinal properties of pharmaceutical composition.

2 cl, 20 tbl, 21 ex

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RU 2 317 819 C2

Authors

Lipton Alan

Uitters Louis Mehri

Grin Dzhonatan

Dates

2008-02-27Published

2002-10-18Filed