FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention describes a method for preparing new derivatives of 1,2,4-triazole of the general formula (I): 
wherein R1 means the group -R3CO or -; -R3SO2; R2 means hydrogen atom, methyl, the group CH2=CH-, phenyl; R3 means methyl, phenyl, 4-MeC6H4. Method involves addition of corresponding alkyl halide to 5-amino-3-[N-R1]-amino-1-phenyl-1,2,4-triazole solution in dimethylsulfoxide, dimethylformamide or N-methylpyrrolidone in the presence of sodium alcoholate. Proposed method can be used in synthesis of medicinal and biologically active substances from inexpensive and available raw being without using the complex technological procedures.
EFFECT: improved preparing method.
2 cl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING 5-AMINO-3-N-R-AMINO-1-R-1,2,4-TRIAZOLE | 2005 |
|
RU2290398C2 |
| METHOD FOR PRODUCTION OF 5-AMINO-1,2,4-TRIASOL-3-YLCARBOXYLIC ACID OR 5-AMINO-1,2,4-TRIASOL-3-YLACETIC ACID ESTERS | 2004 |
|
RU2269521C1 |
| METHOD FOR SYNTHESIS OF 3(5)-PYRIDYL-SUBSTITUTED 5(3)-AMINO-1,2,4-TRIAZOLES | 2009 |
|
RU2412180C1 |
| METHOD FOR PREPARING R-METHYL-DERIVATIVES OF 3,5-DIAMINO-1,2,4-TRIAZOLE | 2005 |
|
RU2292340C1 |
| METHOD FOR PREPARING 2-(3',5'-DIAMINO-1',2',4'-TRIAZOL-1'-YL)-4-R-5-R-1,3-THIAZOLES | 2005 |
|
RU2298553C1 |
| METHOD OF 2-SULPHONILAMINE-1,2,4,-TRIAZOLO[1,5-a] PYRIMIDINES PRODUCTION | 2007 |
|
RU2325390C1 |
| 1-PHENYL-3-ALKYL-5-(O-HYDROXYPHENYL)-1,2,4-TRIAZOLS POSSESSING TRANQUILIZING ACTIVITY | 1983 |
|
SU1280851A1 |
| METHOD OF PRODUCING 5-SUBSTITUTED 1-H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | 2010 |
|
RU2446163C2 |
| METHOD OF PRODUCING 5-HYDROXYALKYL-SUBSTITUTED DERIVATIVES OF 1-PHENYL-1,2,4-TRIAZOLE | 2017 |
|
RU2742885C2 |
| N4-SUBSTITUTED 3-ALKYLSULPHANYL-5-(1,2,4-TRIAZOLE-1-YLMETHYL)-1,2,4-TRIAZOLES, METHOD FOR PRODUCTION THEREOF, FUNGICIDE AND GROWTH REGULATORY COMPOSITION ON THEIR BASIS | 2017 |
|
RU2668212C1 |
