FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to a new compound, i. e. 3-(4-nitrobenzoylmethylene)-1H,4H-hexahydro-2-quinoxalone of the formula (I) 
possessing anti-inflammatory activity. Proposed compound possesses the reduced toxicity.
EFFECT: improved and valuable medicinal properties of compound.
2 tbl, 1 ex
| Title |
Year |
Author |
Number |
| 1-(3-AMINOPROPYL)-3-HYDROXY-5-(4-FLUOROPHENYL)-4-(4-CHLOROBENZOYL)-3-PYRROLINE-2-ONE HYDROCHLORIDE ELICITING ANTI-INFLAMMATORY ACTIVITY |
2004 |
- Gejn V.L.
- Jushkov V.V.
- Kasimova N.N.
- Shuklina N.S.
- Gubanova M.V.
|
RU2259354C1 |
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2005 |
- Gejn Vladimir Leonidovich
- Jushkov Vladimir Viktorovich
- Kasimova Natal'Ja Nurislamovna
- Shuklina Natal'Ja Sergeevna
- Gubanova Marina Vladimirovna
|
RU2303448C2 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY |
2008 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgen'Evich
- Makhmudov Ramiz Ragipovich
- Zalesov Vladimir Vasil'Evich
|
RU2389724C1 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Rubtsov Aleksandr Evgenevich
|
RU2785780C1 |
| 1-(4-METHOXYPHENYL)2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID ETHYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
|
RU2798428C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Sharaveva Iuliia Olegovna
|
RU2784434C1 |
| 1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798468C1 |
| APPLICATION OF 4-(4-BROMOPHENYL)-2-[2-(4-NITROBENZOYL)HYDRAZONO]-4-OXOBUTANOIC ACID AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
|
RU2785781C1 |
| 3-(2'-NAPHTHOYLMETHYLENE)-PIPERAZINONE-2 AND 1-N-PHENYL-3-PHENACYLIDENEPIPERAZINONE-2 SHOWING ANTIINFLAMMATORY ACTIVITY |
1994 |
- Miljutin A.V.
- Safonova N.V.
- Makhmudov R.R.
- Goleneva A.F.
- Andrejchikov Ju.S.
|
RU2067579C1 |
| N-(5-BROMOPYRIDIN-2-YL)-4-OXO-4-(P-TOLYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL) )AMINO)BUT-2-ENAMIDE AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Okoneshnikova Elizaveta Aleksandrovna
|
RU2798426C1 |
