FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to new compound, 1-(3-aminopropyl)-3-hydroxy-5-(4-fluorophenyl)-4-(4-chlorobenzoyl)-3-pyrroline-2-one hydrochloride of the formula:
that elicits an anti-inflammatory activity that allows its using in medicine. Invention describes a method for its preparing.
EFFECT: valuable medicinal properties of compound.
2 tbl, 1 ex
| Title |
Year |
Author |
Number |
| 4-HYDROXY-5-(3-NITROPHENYL)-4-(4-CHLOROBENZOYL)-1-(2-DIETHYLAMINOETHYL)-3-PYRROLINE-2-ONE HYDROCHLORIDE ELICITING ANTI-INFLAMMATORY ACTIVITY |
2005 |
- Gejn Vladimir Leonidovich
- Jushkov Vladimir Viktorovich
- Kasimova Natal'Ja Nurislamovna
- Shuklina Natal'Ja Sergeevna
- Gubanova Marina Vladimirovna
|
RU2303448C2 |
| 3-(4-NITROBENZOYLMETHYLENE)-1H,4H-HEXAHYDRO-2-QUINOXALONE ELICITING ANTI-INFLAMMATORY ACTIVITY |
2004 |
- Gejn Vladimir Leonidovich
- Jushkov Vladimir Viktorovich
- Panina Marina Aleksandrovna
- Shuklina Natal'Ja Sergeevna
- Gubanova Marina Vladimirovna
|
RU2271352C2 |
| 4-OXO-2-{[4-PHENYL-3-(ETHOXYCARBONYL)THIOPHEN-2-YL]AMINO)}-4-(4-FLUOROPHENYL)BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Sharaveva Yuliya Olegovna
|
RU2831129C1 |
| 1,4,5,6-TETRAHYDRO-6-OXO-5-(2-PIPERAZINOETHYL)-4-PHENYL-3-(4-CHLOROPHENYL)PYRROLO[3.4-C]PYRAZOLE DIHYDROCHLORIDE ELICITING HYPOTENSIVE AND ANTI-COAGULANT ACTIVITY |
2006 |
- Gejn Vladimir Leonidovich
- Syropjatov Boris Jakovlevich
- Kasimova Natal'Ja Nurislamovna
- Dozmorova Natal'Ja Viktorovna
- Egorova Anastasija Olegovna
- Ismajlova Natal'Ja Gennad'Evna
|
RU2320661C2 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Rubtsov Aleksandr Evgenevich
|
RU2785780C1 |
| 5-AMINO-3-(MORPHOLINE-4-CARBONYL)-1-(2-OXO-2-(4-FLUOROPHENYL)ETHYLIDENE)-6,7,8,9-TETRAHYDROBENZO[4,5]THIENO[3,2-E]PYRROLO[1,2-A]PYRIMIDIN-2(1H)-ONE, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Parkhoma Kseniya Yurevna
|
RU2831363C1 |
| APPLICATION OF N-(2-OXO-5-(4-CHLOROPHENYL)FURAN-3(2H)-YLYDENE)-4-NITROBENZOHYDRAZIDE AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
|
RU2785782C1 |
| 4-OXO-2-[2-(4-NITROBENZOYL)HYDRAZINYLIDENE]-4-(4-ETHYLPHENYL)-N-PHENETHYLBUTANAMIDE, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2836430C1 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY |
2008 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgen'Evich
- Makhmudov Ramiz Ragipovich
- Zalesov Vladimir Vasil'Evich
|
RU2389724C1 |
| 4-(4-BROMOPHENYL)-4-OXO-2-{[3-ETHOXYCARBONYL)-4,5-DIMETHYLTHIEN-2-YL]AMINO}-2-BUTENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY |
2012 |
- Makhmudov Ramiz Ragibovich
- Rubtsov Aleksandr Evgen'Evich
- Shipilovskikh Sergej Aleksandrovich
|
RU2485112C1 |
