FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to new compound, 1-(3-aminopropyl)-3-hydroxy-5-(4-fluorophenyl)-4-(4-chlorobenzoyl)-3-pyrroline-2-one hydrochloride of the formula:
that elicits an anti-inflammatory activity that allows its using in medicine. Invention describes a method for its preparing.
EFFECT: valuable medicinal properties of compound.
2 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 4-HYDROXY-5-(3-NITROPHENYL)-4-(4-CHLOROBENZOYL)-1-(2-DIETHYLAMINOETHYL)-3-PYRROLINE-2-ONE HYDROCHLORIDE ELICITING ANTI-INFLAMMATORY ACTIVITY | 2005 |
|
RU2303448C2 |
| 3-(4-NITROBENZOYLMETHYLENE)-1H,4H-HEXAHYDRO-2-QUINOXALONE ELICITING ANTI-INFLAMMATORY ACTIVITY | 2004 |
|
RU2271352C2 |
| 1,4,5,6-TETRAHYDRO-6-OXO-5-(2-PIPERAZINOETHYL)-4-PHENYL-3-(4-CHLOROPHENYL)PYRROLO[3.4-C]PYRAZOLE DIHYDROCHLORIDE ELICITING HYPOTENSIVE AND ANTI-COAGULANT ACTIVITY | 2006 |
|
RU2320661C2 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785780C1 |
| APPLICATION OF N-(2-OXO-5-(4-CHLOROPHENYL)FURAN-3(2H)-YLYDENE)-4-NITROBENZOHYDRAZIDE AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785782C1 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2008 |
|
RU2389724C1 |
| 4-(4-BROMOPHENYL)-4-OXO-2-{[3-ETHOXYCARBONYL)-4,5-DIMETHYLTHIEN-2-YL]AMINO}-2-BUTENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2012 |
|
RU2485112C1 |
| APPLICATION OF 4-(4-BROMOPHENYL)-2-[2-(4-NITROBENZOYL)HYDRAZONO]-4-OXOBUTANOIC ACID AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785781C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2784434C1 |
| 1-(4-METHOXYPHENYL)2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID ETHYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2798428C1 |
