METHOD FOR WITHDRAWING INTRAOCULAR NEOPLASMS Russian patent published in 2006 - IPC A61F9/08 A61N5/67 A61K31/409 

FIELD: medicine.

SUBSTANCE: method involves intrastromally introducing chlorine row photosensitizer into tumor in 0.35-0.5% solution in the amount of 0.1-0.5 ml, intravitreally applying to tumor in 1.0-2.0% gel in the amount of 0.2-0.3 ml and intravenously introducing at a dose of 0.5-0.8 mg/kg. Intravenous laser irradiation with wavelength corresponding to maximum light emission absorption on photosensitizer part is concurrently applied with Intravenous photosensitizer introduction during 10-15 min with power of 20-500 mW. Intravenous laser irradiation being over, spectral fluorescence diagnostic of neoplasm is applied. Intravitreal laser irradiation of neoplasm is carried out with wavelength corresponding to maximum light emission absorption on photosensitizer part under power density of 100-120 J/cm². Then, intraocular neoplasm is intravitreally removed. Retina is smoothed with perfluororganic compound. Photosensitizer is repeatedly introduced 7-14 days later after removing neoplasm and spectral fluorescence diagnostic is applied. The fluorescent regions are exposed to laser radiation with wavelength corresponding to maximum light emission absorption on photosensitizer part and power density equal to 50-80 J/cm². The perfluororganic compound is substituted with silicon oil. Intravenous photosensitizer introduction and intravenous laser irradiation of blood are repeated 3 months later.

EFFECT: enabled complete intraocular neoplasm removal; reduced risk of viable tumor cells being retained in operation field or disseminated; reduced risk of relapses and metastases applied; completely stopped tumor growth.

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