METHOD FOR REMOVING INTRAOCULAR NEOPLASMS Russian patent published in 2006 - IPC A61F9/08 A61N5/67 

FIELD: medicine, ophthalmology.

SUBSTANCE: the present innovation deals with removing choroids melanoma. One should fulfill vitrectomy, retinotomy, lance intraocular neoplasm with subsequent substitution of PFOC for silicon oil (SO), intravitreally irradiate melanoma with low-intensity laser radiation with fields circularly from the center towards periphery at wave length being 633 nm at the dosage of 2.5 J or at wave length being 890 nm at the dosage of 1.2 J. After that, intravenously one should inject a photosensitizer (PS) of chlorine group at the dosage of 0.8-1.1 mg/kg for 10 min to keep for about 15-20 min and carry out spectral-fluorescent diagnostics of the neoplasm. In case of fluorescence of intraocular neoplasm it is necessary to perform intravitreal irradiation of the neoplasm with laser radiation with fields circularly from periphery towards the center at overlapping the neighboring fields for 5% of the area. Wave length corresponds to the maximal absorption of light radiation by PS, energy density corresponds to about 100-120 J/sq. cm. Intravitreally one should remove choroids melanoma followed by spreading patient's retina with perfluoroorganic compound (PFOC) to conduct separating endolaserocoagulation of retinotomic part. In about 7-14 d it is necessary to repeat intravenous injection of PS to fulfill spectral-fluorescent diagnostics. Intravitreally in PFOC medium one should irradiate the parts of fluorescence with laser radiation at wave length that corresponds to maximal absorption of light radiation by PS, at energy density being about 80-100 J/sq. cm. After that, one should substitute PFOC for SO. The innovation provides the most complete removal of choroids melanoma, considerable decrease of the risk to keep viable tumor cells in surgical field and dissemination of tumor cells during removal of neoplasms and, also, decreased risk for relapses and metastases.

EFFECT: higher efficiency of removal.

1 cl, 2 ex