BIOTRANSPLANT AND METHOD FOR TREATMENT OF LUNG HYPERTENSION Russian patent published in 2006 - IPC A61K35/28 A61K35/48 C12N5/08 A61P9/12 

Abstract RU 2271817 C1

FIELD: medicine and biopharmacology.

SUBSTANCE: claimed biotransplant contains mesenchyme stem cells (MSC) obtained from fetal, donor or autologous material. Tissue is desagregated, obtained cell suspension is resuspended and cultivated on growth medium containing transferrin, insulin, fibroblast growth factor and heparin to accumulate mature stroma in cells. Method for treatment of lung hypertension includes intravenous drip-feeding of MSC in amount of 50-500 millions cells in 50-100 ml of physiological solution.

EFFECT: method for treatment of improved effectiveness having no undesired side effects.

6 cl

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RU 2 271 817 C1

Authors

Gol'Dshtejn Dmitrij Vadimovich

Makarov Andrej Vital'Evich

Fatkhudinov Timur Khajsamudinovich

Repin Vadim Sergeevich

Shamenkov Dmitrij Alekseevich

Rzhaninova Alla Anatol'Evna

Saburina Irina Nikolaevna

Pulin Andrej Alekseevich

Utjashev Igor' Agljamovich

Bazhanov Nikolaj Aleksandrovich

Dates

2006-03-20Published

2004-08-18Filed