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2 271 819

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IPC

A61K35/36(2006-01-01)

C12N5/08(2006-01-01)

A61P17/14(2006-01-01)

(21) (22)

Application

2004125092/15, 2004-08-18

(24)

Start date

2004-08-18

(22)

Actual filing date

2004-08-18

(45)

Published

2006-03-20

(72)

Inventor

Gol'Dshtejn Dmitrij VadimovichMakarov Andrej Vital'EvichFatkhudinov Timur KhajsamudinovichRepin Vadim SergeevichShamenkov Dmitrij AlekseevichRzhaninova Alla Anatol'EvnaSaburina Irina NikolaevnaPulin Andrej AlekseevichUtjashev Igor' AgljamovichBazhanov Nikolaj AleksandrovichShvetsova Elena Vladimirovna

(73)

Holder

Zao

BIOTRANSPLANT, METHOD FOR PRODUCTION THEREOF (VARIANTS), AND METHOD FOR ALOPECIA TREATMENT Russian patent published in 2006 - IPC A61K35/36 C12N5/08 A61P17/14

Abstract RU 2271819 C1

FIELD: medicine and biopharmacology.

SUBSTANCE: claimed biotransplant contains culture of genetically non-modified mesenchyme stem cells (MSC), including fibroblasts of hair follicule dermal papillae, epithelial cells including ones obtained from hair follicle stem niche. Biotransplant is used in intradermal administration. Method for alopecia treatment includes intradermal administration of biotransplant containing from 10 to 100 millions cells to patient, in procedure room by micropapulic method. Biotransplant is administered in physiological solution with concentration from 1 to 10 millions per 1 ml. Total transplant amount is 1-10 millions depending on lesion area and type of alopecia.

EFFECT: method for alopecia treatment with high reproducibility.

12 cl

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RU 2 271 819 C1

Authors

Gol'Dshtejn Dmitrij Vadimovich

Makarov Andrej Vital'Evich

Fatkhudinov Timur Khajsamudinovich

Repin Vadim Sergeevich

Shamenkov Dmitrij Alekseevich

Rzhaninova Alla Anatol'Evna

Saburina Irina Nikolaevna

Pulin Andrej Alekseevich

Utjashev Igor' Agljamovich

Bazhanov Nikolaj Aleksandrovich

Shvetsova Elena Vladimirovna

Dates

2006-03-20—Published

2004-08-18—Filed