BIOTRANSPLANT FOR TREATMENT OF DEGENERATIVE AND TRAUMATIC DISEASE OF CARTILAGE TISSUE AND METHOD FOR ITS PREPARING Russian patent published in 2007 - IPC A61K35/28 A61K35/32 A61K35/54 A61K31/737 A61P19/02 

FIELD: medicine, biopharmacology.

SUBSTANCE: invention relates to a method for preparing a biotransplant based on combination of low-differentiated (multipotent, cambial, stem) human cells and matrix-carrier. Combined biotransplant for treatment of traumatic and degenerative diseases of cartilage tissue represents the multicomponent, volume, three-dimensional structure comprising low-differentiated human cells and matrix-carrier. Chitosan and/or alginate, and/or collagen are used as a matrix-carrier, and hyaluronic acid, chondroitin sulfate are used as composition additives in the ratio of a basic substance and composition additive, %: (90-99):(1-10), respectively. After termination the process for preparing a carrier suspension of cellular culture of chondroblasts, fibroblasts, bone marrow mesenchymal stem cells, lipid tissue or other origin is added to a carrier of both autologic and allogenic origin. Invention provides enhancing effectiveness of treatment. Invention can be used for enhancing regenerative and reparative properties of cartilage and connective tissues in traumatic and degenerative diseases of joint cartilage.

EFFECT: valuable properties and enhanced effectiveness of biotransplant.

12 cl, 2 ex