SUBSTITUTED 2-ANILINOBENZIMIDAZOLES, THEIR USING AS INHIBITORS OF NA/H-EXCHANGE AND MEDICINAL AGENT COMPRISING THEREOF Russian patent published in 2006 - IPC C07D235/30 A61K31/4184 

Abstract RU 2272031 C2

FIELD: organic chemistry, medicine.

SUBSTANCE: invention describes a compound of the formula (I): representing such compound as 2-(2,6-dichlorophenylamino)-1H-benzimidazol-4-ol and others. Also, invention relates to using these compounds for preparing a medicinal agent used in treatment of diseases associated with inhibition of [Na+/H+]-exchange. Proposed compounds can be used, in particular, in treatment and prophylaxis of impairment of respiratory impulse, acute and chronic renal diseases.

EFFECT: valuable medicinal properties of compounds.

17 cl, 19 ex

Similar patents RU2272031C2

Title Year Author Number
PESTICIDE COMPOSITIONS AND RELATED METHODS 2013
  • Lo Villyam K.
  • Khanter Dzhejms E.
  • Uotson Dzherald B.
  • Patni Akshaj
  • Ijer Pravin S.
  • Boruva Dzhoshodip
RU2654336C2
STIMULATING AGENTS OF GROWTH HORMONE SECRETION 1996
  • Filip A. Karpino
  • Pol A. Dasil'Va Dzhardin
  • Brjus A. Lefker
  • Dzhon A. Rehgehn
RU2172742C2
AMIDES AS MODULATORS OF SODIUM CHANNELS 2014
  • Adida-Rua Sara Sabina
  • Anderson Kori
  • Arumugam Vidzhayalaksmi
  • Asgian Iuliana Lyusi
  • Bear Brajan Richard
  • Termin Andreas P.
  • Dzhonson Dzhejms Filip
RU2658920C2
MODIFIED 2- AND 3-NUCLEOSIDES AND USE THEREOF TO PRODUCE MEDICINAL AGENT, HAVING HEPATITIS C INHIBITING ACTIVITY 2003
  • Sommadossi Zhan-P'Er
  • La Kolla Paolo
  • Storer Richard
  • Gosselin Zhil'
RU2437892C2
MODIFIED 2'- AND 3'-NUCLEOSIDES AND USE THEREOF FOR PREPARING DRUG FOR TREATING FLAVIVIRIDAE INFECTIONS 2011
  • Sommadossi Zhan-P'Er
  • La Kolla Paolo
  • Storer Richard
  • Gosselin Zhil'
RU2483075C2
APOPTOSIS-INDUCING AGENTS FOR TREATING CANCER AND IMMUNE AND AUTOIMMUNE DISEASES 2010
  • Kheksamer Laura
  • Din Khun
  • Ehlmor Stiven V.
  • Kanzer Aaron R.
  • Sun Sjaokhun
  • Sauehrs Ehndrju Dzh.
  • Sallivan Dzherard M.
  • Tao Chzhi-Fu
  • Uehndt Majkl D.
RU2539587C2
PROMEDICINES OF MODIFIED 2'- AND 3'-NUCLEOSIDES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS 2003
  • Sommadossi Zhan-P'Er
  • La Kolla Paolo
  • Storer Richard
  • Gosselin Zhil'
RU2366661C2
FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL 2012
  • Takakhasi Masaki
  • Tanabe Takamasa
  • Ito Mai
  • Nokura Josikhiko
  • Ivata Atsusi
RU2606119C2
TETRASUBSTITUTED BENZENES 2008
  • Shapiro Gideon
  • Chesuort Richard
RU2527177C2
PYRIDONAMIDES AS SODIUM CHANNELS MODULATORS 2014
  • Hadida-Ruah, Sara, Sabina
  • Anderson, Corey
  • Arumugam, Vijayalaksmi
  • Asgian, Iuliana, Luci
  • Bear, Brian, Richard
  • Termin, Andreas, P.
  • Johnson, James, Philip
RU2808424C2

RU 2 272 031 C2

Authors

Khofmajster Armin

Khajnel'T Uve

Lang Khans-Jokhen

Bljajkh Markus

Virt Klaus

Gekle Mikhel'

Dates

2006-03-20Published

2001-11-22Filed