FIELD: pharmaceutical technology, pharmacy.
SUBSTANCE: invention relates to a method for preparing submicron particles of water-insoluble or difficultly water-soluble organic pharmaceutical substance. Method involves dissolving this substance in the first water-mixing solvent, mixing the prepared solution with the second solvent for making pre-suspension and homogenization of prepared pre-suspension or by its ultrasonic oscillation. Method provides preparing particles of size less 2 mcm.
EFFECT: improved preparing method.
32 cl, 17 dwg, 18 ex
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Authors
Dates
2006-03-27—Published
2001-12-20—Filed