FIELD: pharmacy.
SUBSTANCE: invention relates to metronidazol-base antiprotozoan preparation possessing broad spectrum of action with respect to protozoa. Proposed agent is made as tablets based on metronidazol and comprises polyvinylpyrrolidone, filling agent and powdering agent also. Microcrystalline cellulose is used as a filling agent, and a mixture of cross-linked homopolymer of N-vinyl-2-pyrrolidone with the nitrogen content 11-12.8% and poly-(2-oxypyrrolidine-1-ylethylene) with K- viscosity value 22.5-26.7 and taken in the ratio = (1-5):1, respectively, is used as polyvinylpyrrolidone. Invention provides enhancing strength of tablet in combination with its rapid degradation in water.
EFFECT: improved pharmaceutical properties of agent.
1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| CARBAMAZEPIN-BASE DRUG | 2001 |
|
RU2189225C1 |
| METHOD FOR MAKING SIMVASTATIN-CONTAINING TABLETS | 2002 |
|
RU2214242C1 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING S1P RECEPTOR MODULATOR | 2007 |
|
RU2487703C2 |
| METHOD FOR OBTAINING SOLID MEDICINAL FORM OF PREPARATION OF DIURETIC ACTION | 2002 |
|
RU2203063C1 |
| AGENT BASED ON DRY MOTHERWORT EXTRACT AND METHOD FOR PRODUCTION THEREOF | 2015 |
|
RU2589507C1 |
| DOXAZOZINE-BASED PHARMACEUTICAL COMPOSITION | 2001 |
|
RU2190392C1 |
| ANTIVIRAL AGENT AND METHOD OF PREPARATION THEREOF | 2000 |
|
RU2160105C1 |
| SOLID PHARMACEUTICAL COMPOSITION FOR IMPROVEMENT OF MAIL ERECTILITY FUNCTION | 2005 |
|
RU2283650C1 |
| PHARMACEUTICAL DOSED FORM, CONTAINING POLYMER CARRIER COMPOSITION | 2009 |
|
RU2519679C9 |
| INSTANTLY SOLUBLE DOSAGE FORM OF METRONIDAZOLE AND METHOD OF ITS OBTAINING (VERSIONS) | 2021 |
|
RU2797947C2 |
